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Original Article
Statistical Analysis of 1,000 Cases of Kawasaki Disease Patients Diagnosed at a Single Institute
Dae Hwan Hwang, Kyoung Mi Sin, Kyong Min Choi, Jae Young Choi, Jun Hee Sul, Dong Soo Kim
Clin Exp Pediatr. 2005;48(4):416-424.   Published online April 15, 2005
Purpose : To find the risk factors associated with coronory artery lesions, non-responsiveness to intravenous immunoglobulin(IVIG) treatment, and recurrences in Kawasaki disease patients. Methods : We retrospectively analyzed 1,000 Kawasaki disease patients who were admitted to Yonsei University Medical Center from September 1990 to December 2003. We compared between responder and non-responder groups to IVIG treatment as well as between relapsed...
Risk Factors of Nosocomial Rotavirus Infections in Children
Sin Ae Park, Sun Hee Yu, Seon Woong Lim, Kyung Dan Choi
Clin Exp Pediatr. 2005;48(4):395-400.   Published online April 15, 2005
Purpose :Rotavirus is one of the most important causes of nosocomial infections among children. The aim of this study is to determine the risk of nosocomial rotavirus infections and to evaluate the effectiveness of breast-feeding and probiotics in the prevention of nosocomial rotavirus infections. Methods : This study was carried out on admitted children without diarrhea between March 1, 2003 and...
Intrauterine Intraventricular Hemorrhage in Premature Infants
Hyun-Seung Jin, Kyeng-Ah Park, Hyun-Woo Goo, Jong-Hyun Yoon, Ellen Ai-Rhan Kim, Ki-Soo Kim, Soo-Young Pi
Clin Exp Pediatr. 2005;48(1):27-33.   Published online January 15, 2005
Purpose : To determine incidence, characteristics and risk factors associated with intrauterine intraventricular hemorrhage(IU-IVH) among premature infants. Methods : The medical records of infants with intraventricular hemorrhage(IVH) admitted to the neonatal intensive care unit of Asan Medical Center from January 1999 to June 2003 were reviewed retrospectively. Infants whose IVH with cystic change were detected within five days of life were...
The Incidence and Risk Factors of Posttraumatic Seizure in Children
Sue Youn, Mi A Lee, Hwang Min Kim, Byung Ho Cha
Clin Exp Pediatr. 2004;47(11):1198-1204.   Published online November 15, 2004
Purpose : The goal of our study was to identify the incidence and clinical, neurophysiological and neuroradiological variables with predictive value for posttraumatic seizure(PTS). Methods : The medical records of 625 children with head traumas under 15-year-old who were admitted to the Wonju Christian Hospital, from January, 1993 to January, 2002 were retrospectively reviewed. Among them, 472 patients were included...
A Multivariate Analysis of Risk Factors of Renal Involvement in Henoch-Sch nlein Purpura
Min Jee Jeoung, Hyung Eun Yim, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
Clin Exp Pediatr. 2004;47(4):405-411.   Published online April 15, 2004
Purpose : Long-term prognosis of Henoch-Sch nlein purpura(HSP) is determined by the existence and severity of renal involvement. We evaluated the relationship between various clinical features of HSP and the development of renal involvement using univariate and multivariate analyses for early detection and proper management of HSP nephritis. Methods : We performed a retrospective study of 200 children who were diagnosed...
Clinical Characteristics and Epidemiologic Study of Infection Due to Extended Spectrum β-Lactamase Producing Organism in a Neonatal Intensive Care Unit
Nu-Lee Jun, Jae-Woo Im, Hyun-Kyung Park, Mi-Na Kim, Ellen Ai-Rhan Kim, Ki-Soo Kim, Soo-Young Pi
Clin Exp Pediatr. 2004;47(4):373-379.   Published online April 15, 2004
Purpose : The extended-spectrum β-lactamase(ESBL) producing organism have emerged to be an important pathogen in neonatal intensive care unit(NICU). This study was conducted to investigate incidence, characteristics and risk factors associated with ESBL organism among newborns in NICU. Methods : The subjects included 98 newborns admitted to NICU at Asan Medical Center between September 1998 to July 2002, from whom...
Risk Factors of Nephrocalcinosis in Very Low Birth Weight(VLBW) Infants
Gyu Hong Shim, Jin A Lee, Yun Jung Shin, Ee Kyung Kim, June Dong Park, Beyong Il Kim, Jung Hwan Choi
Clin Exp Pediatr. 2004;47(3):275-281.   Published online March 15, 2004
Purpose : Nephrocalcinosis in very low birth weight(VLBW) infants were known to be caused by a longer duration of furosemide use. However, etiologies, pathogenesis and risk factors remain unclear. Therefore, we examined the incidence and risk factors of nephrocalcinosis in VLBW infants retrospectively. Methods : Inborn babies of birth weights less than 1,500 gm were examined retrospectively. Data were reviewed on...
Outcome after Discontinuation of Antiepileptic Drugs in Well Controlled Epileptic Children - Recurrence and Related Risk Factors
Hyo-Bin Kim, Su Jeong You, Tae-Sung Ko
Clin Exp Pediatr. 2004;47(1):66-75.   Published online January 15, 2004
Purpose : There has been no exact criteria established for when to discontinue antiepileptic drugs (AEDs) in epileptic children who had been well controlled for a long period. This study was undertaken to evaluate the recurrence rate and predictive risk factors of relapse after discontinuation of AEDs in epileptic children who had been seizure-free. Methods : We retrospectively studied 294 children...
Risk Factors for the First-Year Relapse in Children with Nephrotic Syndrome
Hye Kyoung Shin, Ji Hee Kim, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
Clin Exp Pediatr. 2003;46(9):889-892.   Published online September 15, 2003
Purpose : This study aimed to evaluate risk factors of the first year relapse in children with nephrotic syndrome(NS) without the need for biopsy. Methods : We reviewed, retrospectively, 78 children diagnosed with steroid responsive nephrotic syndrome between July 1997 and June 2002. Median years to follow up were 4.4 years(range : 1-5 years). We divided the patients into two groups(group...
Recurrence and Follow-up after Urinary Tract Infection
Ji Hee Kim, Hye Kyung Shin, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
Clin Exp Pediatr. 2003;46(6):561-565.   Published online June 15, 2003
Purpose : Urinary tract infection(UTI) is the most common bacterial infectious disease that may induce severe renal injury unless early diagnosis and appropriate treatment are performed. If recurrent UTI is prevented, renal injury can be also reduced. Therefore, we studied the risk factors of recurrent UTI in children. Methods : We performed a retrospective study of 168 children(58 girls and 110...
Colon Perforation during Air Enema Reduction of Intussusception
Yong Kuk Kim, Hae Ra Im, Gwang Hoon Lee, Soo Jin Han, Yong Han Sun, Eell Ryoo, Kang Ho Cho, Hann Tchah, Hak Soo Lee
Clin Exp Pediatr. 2003;46(1):37-41.   Published online January 15, 2003
Purpose : Although air enema reduction has been known as a good method of diagnosis and treatment of intussusception, it could develop colon perforation. However, there have been few studies about this complication. So we analyzed the risk factors of colon perforation during air enema reduction in patients with intussusception. Methods : We reviewed the charts of 12 colon perforation patients...
A Follow-Up Study after Discontinuation of Antiepileptic Drug Therapy in Children with Well-Controlled Epilepsy : The Factors that Influence Recurrence
Sa Jun Chung, Hye Jeon Chung, Young Mi Choi, Eu Hyun Cho
Clin Exp Pediatr. 2002;45(12):1559-1570.   Published online December 15, 2002
Purpose : There has been no exact answer to the question of when to discontinue antiepileptic drugs(AEDs) in children with well-controlled epilepsy for a long period. This study is about the risk factors of relapse after withdrawal of AEDs in seizure(Sz)-free patients to show a guideline for discontinuation of AEDs. Methods : One hundred and sixty-nine children were diagnosed as epileptic...
Recurrence Rate of Febrile Seizures by Combining Risk Factors
Su Jung Moon, Gu Ken Sun, Eun Young Kim, Kyong Hee Na, Sun Young Park, Kyoung Sim Kim, Yong Wook Kim
Clin Exp Pediatr. 2002;45(11):1403-1410.   Published online November 15, 2002
Purpose : In previous studies, various risk factors for recurrent febrile seizures have been identified. But none of these risk factors alone could sufficiently discriminate children at high or low risk for recurrent seizures. Therefore, we tried to identify patients at high risk of recurrent febrile seizures by combining risk factors. Methods : Two hundred and four children who had...
Prevalence and Risk Factors of Candida Sepsis in Neonatal Intensive Care Unit
Ic Sun Choi, Suk Hwan Lim, Chang Yee Cho, Young Youn Choi, Tai Ju Hwang
Clin Exp Pediatr. 2002;45(7):836-846.   Published online July 15, 2002
Purpose : With the development of neonatal intensive care and the increased use of systemic antibiotics, candida sepsis has become one of the most important causes of neonatal morbidity and mortality. The purpose of this study was to investigate the prevalence rate and its associated risk factors. Methods : We retrospectively reviewed medical records of 28 cases with candida sepsis who...
Clinical Studies of Cerebral Palsy
Won Sik Kang, Kyong Whoon Cheon, Byeong Hee Son, Sung Won Kim
Clin Exp Pediatr. 2002;45(4):512-518.   Published online April 15, 2002
Purpose : Cerebral palsies are the most common and severe motor disabilities in childhood. There is currently increased interest in their occurrence and patterns of likely cause for a variety of reasons. Therefore, a retrospective study was carried out to understand the clinical features of cerebral palsy. Methods : A retrospective chart review was conducted of all children with cerebral palsy...
Classification and Risk Factors for Chronic Lung Disease(CLD) of Prematurity : Classical CLD Versus Atypical CLD
Chang Won Choi, Beyong Il Kim, Heui Seung Jo, Jun Dong Park, Chong Jae Kim, Bo Hyun Yoon, Jung-Hwan Choi
Clin Exp Pediatr. 2001;44(11):1222-1232.   Published online November 15, 2001
Purpose : We tried to classify the different type of CLD and assess the risk factors for classical CLD and atypical CLD. Methods : Retrospective cohort analysis was done in 120 preterm infants with birth weights less than 1,500 g who were admitted to NICU in Seoul National University Children's Hospital between Jan. 1993 and Dec. 1998 and survived more...
A Clinical Study for Risk Factors of Cystic Periventricular Leukomalacia
Ji Eun Kim, Su Jin Kim, Woo Taek Kim
Clin Exp Pediatr. 2001;44(6):627-634.   Published online June 15, 2001
Purpose : It is very important to study the individual risk factors which cause periventricular leukomalacia(PVL) and those which affect the process of cystic formation from liquefied periventricular white matter, in order to prevent and permit early diagnosis of cystic PVL that contributes to mortality and neurologic sequelaes in preterm infants. Therefore, the present study was designed to assess the...
Risk Factors of Renal Scar After Acute Pyelonephritis in Children
Chur Woo You
Clin Exp Pediatr. 2001;44(1):54-61.   Published online January 15, 2001
Purpose : In this study we re-evaluated the known risk factors of pyelonephritic scarring in children. Methods : A prospective study was performed on 36 acute pyelonephritis(APN) patients who were diagnosed as first acute pyelonephritis on 99mTc-DMSA scan between September 1998 and March 2000 in Masan Samsung Hospital. According to the prescence of remnant lesions on the 99mTc-DMSA scan performed...
Risk Factors for Neonatal Sepsis in Premature Infants Admitted to Neonatal Intensive Care Unit
Chang-Ryul Kim, Jae-Won Oh, Myung-Kul Yum, Soo-Jee Moon
Clin Exp Pediatr. 2000;43(9):1174-1179.   Published online September 15, 2000
Purpose : The purpose of this study is to find out the risk factors of sepsis except the prematurity itself. Methods : Seventy-seven premature infants less than 37 weeks of gestation, who were admitted to the neonatal intensive care unit of Hanyang University Kuri Hospital between July 1995 and December 1996, were enrolled in this study. All 77 premature infants, 14...
Analysis of Risk Factors of Readmission to Hospital for Pediatric Asthma
Kyung Lim Yoon, Young Ho Rah, Chong-Woo Bae, Sa Jun Chung
Clin Exp Pediatr. 2000;43(4):556-560.   Published online April 15, 2000
Purpose : The admission rates for pediatric asthma are increasing annually and are partially responsible for the increased rates of readmission. Selections of children with a high-risk of readmission and aggressive treatments of them may improve treatment outcome and cost- effectiveness. The purpose of this study is to evaluate the risk factors affecting readmission in cases of bronchial asthma in...
Clinical Analysis and Comparison of Kawasaki Disease between Patients Younger than One Year of Age and Those over One Year of Age
Hee-Sun Chung, Kyung-Yil Lee, Ji-Whan Han, Sang-Won Cha, Dong-Joon Lee, Kyung-Tai Whang
Clin Exp Pediatr. 1999;42(7):936-942.   Published online July 15, 1999
Purpose : To identify the risk factors for coronary sequelae in Kawasaki disease, we analyzed and compared the clinical features and laboratory findings of Kawasaki disease in patients younger than one year of age with those over one year of age. Methods : A retrospective chart review was conducted of all children with Kawasaki disease who were admitted to the...
The Risk Factors of Renal Scar in Childhood Acute Pyelonephritis
Soo Ja Hwang, Seung Joo Lee
Clin Exp Pediatr. 1999;42(4):545-552.   Published online April 15, 1999
Purpose : To observe the risk factors of renal scar in children with first acute pyelonephritis (APN) who had photopenic defects on initial 99mTc-DMSA spect renal scan. Methods : Forty-seven children with first APN(M : F=33 : 14) who were admitted to Ewha Womans University Hospital from September, 1993 to Febrary, 1998, were divided into renal scar group(N=17, Kidney unit(KU)=18) and...
A Clinical Study for the Time of Development and Risk Factors of Retinopathy of Prematurity
Eun Ae Park, Gyoung Hee Kim
Clin Exp Pediatr. 1997;40(7):945-954.   Published online July 15, 1997
A Study on Clinical Application of Harada's Scoring Method to Kawasaki Disease - Suggesting the revision of the criteria for IVGG treatment of KD in Korea -
Byoung Kil Han, Hyong Shin Lee, Hong Ryang Kil, Heon-Seok Han, Jae Ho Lee, Young Hun Chung
Clin Exp Pediatr. 1997;40(4):539-548.   Published online April 15, 1997
Purpose : We performed a study on clinical benefits of Harada's scoring method, problems of present criteria and requirement of the revision of that criteria for intrvenos γ-globulin(IVGG) treatment of Kawasaki disease(KD) in Korea. Methods : The patients of 104 cases who visited to Department of Pediatrics of Chungnam National University Hospital and diagnosed as KD were objective group. We classified the...
Incidenceand Risk Factorsof the Retinopathy of Prematurity
June Dong Park, Jung Hae Kweon, Woong Heum Kim, Beyong Il Kim, Jung-Hwan Choi, Chong Ku Yun, Sang In Khwarg, Young Suk Yu
Clin Exp Pediatr. 1996;39(3):326-337.   Published online March 15, 1996
Purpose : Retinopathy of prematurity(ROP) continues to be a serious problem in infants who survived with neonatal intensive care. Nevertheless, there is neither available data about the incidence of ROP which may be the basis of the epidemiology, nor analysis of the risk factors of ROP in Korea. The purpose of this retrospective study was to evaluate the incidence of...
Ischemic Hepatitis in Children after Cardiac Operation -Analysis of Clinical Characteristics, Risk Factors and Outcome-
Kyung Mo Kim, Jeong Kee Seo
Clin Exp Pediatr. 1995;38(11):1540-1546.   Published online November 15, 1995
Purpose : We have experienced frequently the ischemic hepatitis after cardiac operations which shows rapid striking rise of transaminase. But the ischemic hepatitis in children after cardiac operation is not defined yet in Korea. We examined the clinical characteristics and analyzed the risk factors and outcome in 20 children who showed typical clinical course of ischemic hepatitis after cardiac operation. Methods...
Incidence and Perinatal Risk Factors of Respiratory Distress Syndrome of Newborn
Yun Sil Chang, Beyong Il Kim, Jung-Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1994;37(8):1065-1077.   Published online August 15, 1994
Over a continuous 4-year period, from January 1989 till December 1992, 7,100 infants were born in Department of Obstetrics and admitted to Nursery or Neonatal Intensive Care Unit of Department of Pediatrics of Seoul National University Children's Hospital. Among them, 126 cases were diagnosed as respiratory distress syndrome (RDS) of newborn. The total incidence of RDS among all the newborns(inborn)was 1.77%....
Risk Factors and Outcome of Bronchopulmonary Dysplasia
Beyong Il Kim, Yun Sil Chang, Dong Woo Son, Hae Kyung Han, Jung-Hwan Choi, Chong Ku Yun, In One Kim, Kyung Mo Yeon, Je G. Chi
Clin Exp Pediatr. 1994;37(1):78-88.   Published online January 15, 1994
The 45 neonates with bronchopulmonary dysplasia among 355 neonates who were managed with mechanical ventilation and oxygen therapy in NICU of Seoul National University Chhildren's Hospital from January 1, 1968 to December 31, 1991, were analyzed for risk factors and outcome. The results were as follows: 1) The incidence of bronchopulmonary dysplasia was 12.7% 2) Respiratory Distress Syndrome was most common underlying problem. 3)...
Clinical Study of Febrile convulsion and Factors Related to Recurrence
Jong Gyun Kim, Keon Su Rhee, Young Hun Chung
Clin Exp Pediatr. 1994;37(1):1-8.   Published online January 15, 1994
We have reserched the relationship of their clinical pictures and factors related to the risk of recurrence of 75 patients with simple or complex febrile convulsions, who were admitted to the Department of Pediatrics, Chungnam National University Hospital from January 1987 to July 1991. The 75 patient were followed up and consisted of the 55 patients with initial or non-recurrent...
The Risk of Seizure Recurrence of Pediatric Epileptic Patients While Receiving Anticonvulsant Drugs Treatment
Dae Sung Hwang, Byung Hyun Kim, Kwang Soo Oh, Yeon Kyun Oh, Hyang Suk Yoon, Jong Duck Kim
Clin Exp Pediatr. 1993;36(9):1271-1278.   Published online September 15, 1993
To evaluate the risk and factors associated with seizure recurrence on children with epilepsy while receiving the adequate anticonvulsant treament, we studied 58 patients with newly diagnosed epilepsy who were followed prospectively for a median of 26 months (range 7 to 54). The results were as follows: 1) Forty-four of the 58 patients (75.9%)had recurrence...
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